Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.43 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306592 | 0.83 | HTR2A (0.59) | HTR2AHRH1TDP1TAAR1AOC3 | |
| SCHEMBL7306585 | 0.83 | HTR2A (0.59) | HTR2AHRH1TDP1TAAR1AOC3 | |
| SCHEMBL11648376 | 0.81 | HTR2A (0.44) | HTR2AHRH1TDP1AOC3GABBR2 | |
| SCHEMBL19090082 | 0.77 | TAAR1 (0.56) | HTR2AHRH1TAAR1AOC3GABBR2 | |
| SCHEMBL2086299 | 0.77 | TAAR1 (0.56) | HTR2AHRH1TAAR1AOC3GABBR2 | |
| SCHEMBL19294780 | 0.77 | TAAR1 (0.56) | HTR2AHRH1TAAR1AOC3GABBR2 | |
| SCHEMBL11648380 | 0.76 | HTR2A (0.40) | HTR2AHRH1TDP1AOC3GABBR2 | |
| SCHEMBL28040042 | 0.76 | TAAR1 (0.65) | HTR2ATAAR1AOC3GABBR2GABBR1 | |
| Hydrochloric Acid SCHEMBL3032167 | 0.76 | TAAR1 (0.54) | HTR2AHRH1TAAR1GABBR2GABBR1 | |
| SCHEMBL8754723 | 0.75 | HTR2A (0.70) | HTR2AHRH1TDP1AOC3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4014884-A | ANTIARRHYTHMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |