Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.46 |
| ▸ | MAOA | P21397 | 11/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29282570 | 0.85 | MAOB (0.51) | MAOBMAOAPRKCIHSD17B1BAZ2B | |
| SCHEMBL11872289 | 0.77 | MAOB (0.56) | MAOBMAOAPRKCIHSD17B1BAZ2B | |
| SCHEMBL5671334 | 0.76 | KDM4E (0.47) | AR | |
| SCHEMBL4811389 | 0.75 | ALDH1A1 (0.50) | MAOBHSD17B1GRM5 | |
| Hydrochloric Acid SCHEMBL11463421 | 0.75 | MAOB (0.54) | MAOBMAOAPRKCIHSD17B1BAZ2B | |
| SCHEMBL27844076 | 0.75 | MAOA (0.52) | MAOBMAOAPRKCIHSD17B1BAZ2B | |
| SCHEMBL11732033 | 0.74 | BAZ2B (0.56) | MAOBMAOAPRKCIHSD17B1BAZ2B | |
| SCHEMBL9222772 | 0.74 | MAOB (0.69) | MAOBMAOA | |
| SCHEMBL14741324 | 0.73 | MAOB (0.51) | MAOBMAOAPRKCIHSD17B1BAZ2B | |
| SCHEMBL32691764 | 0.73 | GRM5 (0.55) | MAOBMAOAPRKCIHSD17B1BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016281-A | Tetralone and indanone compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-04-05 | — | — | US | disclosed |