Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12756960 | 0.88 | POLB (1.00) | POLBTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL6023593 | 0.86 | TDP1 (1.00) | POLBTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL14520778 | 0.85 | ALDH1A1 (0.63) | POLBTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL10805444 | 0.82 | ALDH1A1 (0.63) | POLBTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL1490952 | 0.81 | HPGD (0.76) | POLBTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL12124360 | 0.80 | HPGD (1.00) | POLBTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL1694937 | 0.80 | ALDH1A1 (0.64) | POLBTDP1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL13212973 | 0.80 | TDP1 (0.73) | POLBTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL31396762 | 0.79 | POLB (0.71) | POLBTDP1ALDH1A1HPGDTSHR | |
| SCHEMBL28851995 | 0.79 | POLB (0.71) | POLBTDP1ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054576-A | Insect repellant compounds | STAUFFER CHEMICAL COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4028411-A | Insect repellent dimethylbenzamides | STAUFFER CHEMICAL COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-3966806-A | DIMETHYLBENZENE AMIDES | STAUFFER CHEMICAL COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3966809-A | DIMETHYLBENZENE AMIDES | STAUFFER CHEMICAL COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3960922-A | INSECT REPELLENTS | STAUFFER CHEMICAL COMPANY (US) | 1976-06-01 | — | — | US | disclosed |