Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CDC42 | P60953 | 1/20 | 0.46 |
| ▸ | RAC1 | P63000 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11734040 | 0.94 | POLB (0.53) | POLBSMYD3PTGS2PTGS1AKR1C3 | |
| SCHEMBL11737004 | 0.91 | POLB (0.56) | POLBSMYD3PTGS2PTGS1AKR1C3 | |
| SCHEMBL11737814 | 0.87 | POLB (0.54) | POLBSMYD3PTGS2PTGS1AKR1C3 | |
| SCHEMBL11730090 | 0.85 | POLB (0.72) | POLBSMYD3PTGS2PTGS1AKR1C3 | |
| SCHEMBL11737850 | 0.83 | POLB (0.65) | POLBSMYD3PTGS2PTGS1AKR1C3 | |
| SCHEMBL11732002 | 0.82 | POLB (0.60) | POLBSMYD3PTGS2PTGS1AKR1C3 | |
| Hydrochloric Acid SCHEMBL11736628 | 0.80 | ABCB11 (0.46) | POLBSMYD3PTGS2PTGS1AKR1C3 | |
| SCHEMBL11278320 | 0.75 | POLB (0.77) | POLBSMYD3PTGS2PTGS1AKR1C3 | |
| SCHEMBL11733421 | 0.75 | ABCB11 (0.45) | POLBPTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL11739546 | 0.73 | ABCB11 (0.51) | POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4028366-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-06-07 | — | — | US | claimed |
| US-4028366-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-06-07 | — | — | US | disclosed |
| US-4005093-A | ANTI-INFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-01-25 | — | — | US | disclosed |