Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11737333 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TAS2R38HSD17B10GAA | |
| SCHEMBL11739038 | 0.87 | GAA (0.40) | ALDH1A1CYP3A4GAAMAPTKMT2A | |
| SCHEMBL11739026 | 0.87 | GAA (0.40) | ALDH1A1CYP3A4GAAMAPTKMT2A | |
| SCHEMBL11738687 | 0.84 | SMN1; SMN2 (0.42) | ALDH1A1CYP3A4KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11738682 | 0.84 | SMN1; SMN2 (0.42) | ALDH1A1CYP3A4KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11732291 | 0.79 | GAA (0.44) | ALDH1A1GAAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11732301 | 0.79 | GAA (0.44) | ALDH1A1GAAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11736795 | 0.78 | — | — | |
| SCHEMBL11736800 | 0.78 | — | — | |
| SCHEMBL11730379 | 0.77 | ALOX5 (0.39) | ALDH1A1CYP3A4GAASMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4028344-A | FOAMING AGENTS, FREE RADICAL INITIATORS | PENNWALT CORPORATION (US) | 1977-06-07 | — | — | US | disclosed |