Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11738911 | 0.95 | MAPT (0.31) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11738912 | 0.95 | MAPT (0.31) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7327523 | 0.79 | PSEN1 (0.30) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7327942 | 0.76 | MAPT (0.33) | MAPT | |
| SCHEMBL7356723 | 0.76 | MAPT (0.33) | MAPT | |
| SCHEMBL7327933 | 0.76 | MAPT (0.33) | MAPT | |
| SCHEMBL7326534 | 0.76 | SLC6A3 (0.35) | — | |
| SCHEMBL7326538 | 0.76 | SLC6A3 (0.35) | — | |
| SCHEMBL7333402 | 0.74 | IDO1 (0.39) | — | |
| SCHEMBL7333528 | 0.74 | IDO1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061746-A | Lactamimide inhibitors of gastrointestinal hypersecretion | RICHARDSON-MERRELL INC. (US) | 1977-12-06 | — | — | US | disclosed |