Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11736483 | 0.90 | LMNA (0.60) | LMNAMEN1KMT2APDE4APDE4B | |
| Bromide SCHEMBL11739763 | 0.89 | LMNA (0.58) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL11737199 | 0.84 | LMNA (0.50) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL11740959 | 0.81 | LMNA (0.43) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL11739312 | 0.78 | PDE4A (0.49) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL12595727 | 0.77 | LMNA (0.66) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL11742793 | 0.77 | LMNA (0.56) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL11739470 | 0.76 | LMNA (0.49) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL11720302 | 0.75 | LMNA (0.59) | LMNAMEN1KMT2APDE4APDE4B | |
| SCHEMBL10897130 | 0.73 | LMNA (0.51) | LMNAMEN1KMT2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052395-A | AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES | SANKYO COMPANY LIMITED (JA) | 1977-10-04 | — | — | US | disclosed |