Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 5/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11734946 | 0.93 | POLB (0.56) | POLBTDP1HPSELMNABRAF | |
| SCHEMBL15315484 | 0.91 | POLB (0.54) | POLBTDP1HPSELMNABRAF | |
| SCHEMBL1099442 | 0.88 | POLB (0.61) | POLBTDP1HPSESRD5A2LMNA | |
| SCHEMBL29394890 | 0.88 | POLB (0.61) | POLBTDP1HPSESRD5A2LMNA | |
| SCHEMBL11738616 | 0.84 | HPSE (0.48) | POLBTDP1HPSELMNABRAF | |
| SCHEMBL15294833 | 0.81 | MAPK1 (0.63) | POLBTDP1HPSELMNABRAF | |
| SCHEMBL5020549 | 0.79 | MAPK1 (0.61) | POLBTDP1HPSELMNABRAF | |
| SCHEMBL15294834 | 0.79 | MAPK1 (0.61) | POLBTDP1HPSELMNABRAF | |
| SCHEMBL13345892 | 0.79 | MAPK1 (0.55) | POLBTDP1LMNABRAFHDAC1 | |
| SCHEMBL4738181 | 0.79 | POLB (0.61) | POLBTDP1HPSESRD5A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005134-A | POLYETHERS, POLYIMIDES | GENERAL ELECTRIC COMPANY (US) | 1977-01-25 | — | — | US | disclosed |