Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | PIM1 | P11309 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11738995 | 0.89 | SMN1; SMN2 (0.46) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL11655510 | 0.83 | SMN1; SMN2 (0.46) | KMT2ALMNAHPGDSMN1; SMN2IDO1 | |
| SCHEMBL11571230 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1HPGDSMN1; SMN2MAPTPDE3B | |
| SCHEMBL11743380 | 0.79 | SMN1; SMN2 (0.43) | KMT2ALMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11572086 | 0.79 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2MAPTPDE3BPDE3A | |
| SCHEMBL11741860 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11657483 | 0.78 | SMN1; SMN2 (0.59) | LMNAALDH1A1HPGDSMN1; SMN2IDO1 | |
| SCHEMBL11702077 | 0.77 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2IDO1MAPTPDE3B | |
| SCHEMBL4883210 | 0.76 | PDE3B (0.54) | LMNASMN1; SMN2MAPTPDE3BPDE3A | |
| SCHEMBL11634656 | 0.76 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2MAPTPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052395-A | AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES | SANKYO COMPANY LIMITED (JA) | 1977-10-04 | — | — | US | disclosed |