Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11738805 | 0.84 | MAPK1 (0.50) | SRD5A2ELANEHPGDRAB9AMEN1 | |
| SCHEMBL14770341 | 0.83 | ALDH1A1 (0.54) | ALDH1A1SRD5A2ELANEHPGDRAB9A | |
| SCHEMBL9184984 | 0.82 | TSHR (0.50) | ALDH1A1SRD5A2HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL477440 | 0.80 | AOC3 (0.57) | ALDH1A1LMNACES2CES1L3MBTL1 | |
| SCHEMBL112589 | 0.80 | AOC3 (0.57) | ALDH1A1LMNACES2CES1L3MBTL1 | |
| SCHEMBL9334567 | 0.80 | AOC3 (0.57) | ALDH1A1LMNACES2CES1L3MBTL1 | |
| SCHEMBL11740260 | 0.79 | GABBR2 (0.48) | ALDH1A1HPGDRAB9ANPC1KMT2A | |
| SCHEMBL28587552 | 0.79 | ALDH1A1 (0.58) | ALDH1A1SRD5A2ELANEHPGDRAB9A | |
| SCHEMBL2859236 | 0.78 | ALDH1A1 (0.64) | ALDH1A1SRD5A2ELANEHPGDRAB9A | |
| SCHEMBL22311660 | 0.77 | ACACB (0.45) | ALDH1A1SRD5A2ELANEHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051261-A | HYPOLIPIDEMIC, ANTIDIABETIC | SANDOZ, INC. (US) | 1977-09-27 | — | — | US | disclosed |