Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.30 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14185030 | 0.76 | NOS3 (0.59) | ALDH1A1TP53NOS3NOS2KMT2A | |
| SCHEMBL11738180 | 0.76 | GLP1R (0.38) | ALDH1A1TP53KIF18ANOS3NOS2 | |
| SCHEMBL26538070 | 0.74 | MAPT (0.41) | ALDH1A1TP53KDM4E | |
| SCHEMBL23768159 | 0.73 | ALDH1A1 (0.50) | ALDH1A1NOS2KMT2AHPGDKDM4E | |
| SCHEMBL11723530 | 0.71 | CCNE2 (0.32) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL15907428 | 0.69 | PDE4A (0.38) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL9284715 | 0.67 | SMN1; SMN2 (0.43) | CCNE2CCNE1CDK2KMT2A | |
| SCHEMBL23129866 | 0.67 | KMT2A (0.36) | ALDH1A1TP53NOS3NOS2KMT2A | |
| SCHEMBL23988962 | 0.67 | DHODH (0.41) | ALDH1A1CDK2KMT2AKCNH2 | |
| SCHEMBL11723495 | 0.66 | CCNE2 (0.33) | CCNE2CDK4CCND1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052510-A | 4-ALKYL-2,6-DI(SECONDARY OR TERTIARY ALKYLAMINO) PYRIDINES, COMPOSITIONS THEREOF AND METHODS FOR TREATING DIABETES AND OBESITY | SANDOZ, INC. (US) | 1977-10-04 | — | — | US | disclosed |