Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746767 | 0.84 | CA12 (0.54) | PIM1L3MBTL1HSD17B10POLBTDP1 | |
| SCHEMBL18384672 | 0.80 | PDE4A (0.55) | PIM1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL10801943 | 0.76 | PIM1 (0.56) | PIM1L3MBTL1HSD17B10POLBTDP1 | |
| SCHEMBL11746683 | 0.75 | ALDH1A1 (0.47) | PIM1L3MBTL1HSD17B10POLBTDP1 | |
| SCHEMBL11741049 | 0.74 | ALDH1A1 (0.47) | PIM1L3MBTL1HSD17B10POLBTDP1 | |
| SCHEMBL11745737 | 0.74 | PDE4A (0.50) | PIM1L3MBTL1HSD17B10POLBTDP1 | |
| SCHEMBL4093886 | 0.73 | PIM1 (0.46) | PIM1HSD17B10TDP1ALDH1A1KDM4E | |
| SCHEMBL17864632 | 0.73 | MCL1 (0.46) | PIM1L3MBTL1HSD17B10POLBTDP1 | |
| SCHEMBL11296017 | 0.72 | HSD17B10 (0.54) | PIM1L3MBTL1HSD17B10POLBTDP1 | |
| SCHEMBL3608940 | 0.71 | EDNRA (0.55) | PIM1L3MBTL1HSD17B10PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009994-A | Process and product of optical brightening with quaternized benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1977-03-01 | — | — | US | disclosed |
| US-3940417-A | Quaternised benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |