Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 3/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17843583 | 0.79 | RARA (0.50) | MCL1KDM4EKMT2APIM1CSNK2A1 | |
| SCHEMBL17864631 | 0.77 | CA12 (0.36) | MCL1KDM4EKMT2AMAPTHSD17B10 | |
| SCHEMBL28137256 | 0.74 | THRA (0.49) | MCL1KDM4EKMT2APIM1CSNK2A1 | |
| SCHEMBL17843598 | 0.74 | RARA (0.49) | MCL1KDM4EKMT2APIM1CSNK2A1 | |
| SCHEMBL17843572 | 0.74 | RARA (0.50) | MCL1KDM4EKMT2APIM1CSNK2A1 | |
| SCHEMBL6292875 | 0.73 | MCL1 (0.49) | MCL1KDM4EKMT2APIM1CSNK2A1 | |
| SCHEMBL11739986 | 0.73 | PIM1 (0.50) | KDM4EKMT2APIM1MAPTHSD17B10 | |
| SCHEMBL11743352 | 0.70 | KDM4E (0.52) | MCL1KDM4EKMT2APIM1CSNK2A1 | |
| SCHEMBL11741049 | 0.69 | ALDH1A1 (0.47) | KDM4EKMT2APIM1MAPTHSD17B10 | |
| SCHEMBL11830321 | 0.69 | CSNK2A1 (0.59) | MCL1KDM4EKMT2APIM1CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592219-B | Compound, optical film and method for making optical film | 住友化学株式会社 | 2017-04-12 | — | — | CN | disclosed |
| WO-2016097004-A1 | BICYCLOHETEROARYL-HETEROARYL-BENZOIC ACID COMPOUNDS AS RETINOIC ACID RECEPTOR BETA (RARβ) AGONISTS | KING'S COLLEGE LONDON (GB) | 2016-06-23 | — | — | WO | disclosed |