Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836536 | 0.98 | ALDH1A1 (0.71) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL11735393 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL7461107 | 0.75 | KDM4E (0.68) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL93858 | 0.73 | BCL2L1 (1.00) | RAB9ABCL2L1CA12CA1CA2 | |
| SCHEMBL29438783 | 0.73 | BCL2L1 (1.00) | RAB9ABCL2L1CA12CA1CA2 | |
| SCHEMBL11730860 | 0.72 | ALDH1A1 (0.52) | ALDH1A1HPGDGAASMN1; SMN2POLB | |
| SCHEMBL11732800 | 0.72 | ALDH1A1 (0.52) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL443833 | 0.72 | BCL2L1 (0.96) | RAB9ABCL2L1CA12CA1CA2 | |
| SCHEMBL9578460 | 0.69 | ALDH1A1 (0.59) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL11734831 | 0.69 | HDAC3 (0.50) | ALDH1A1HPGDMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018891-A | INHIBITORS OF ANTIGEN-ANTIBODY REACTIONS | RICHARDSON-MERRELL INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-3960892-A | ANTIGEN-ANTIBODY REACTION INHIBITION | RICHARDSON-MERRELL INC. (US) | 1976-06-01 | — | — | US | disclosed |