Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.80 |
| ▸ | MEN1 | O00255 | 9/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.80 |
| ▸ | MAPT | P10636 | 8/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11740240 | 1.00 | ALDH1A1 (0.80) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL1227106 | 0.89 | MAPT (1.00) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6003482 | 0.84 | MAPT (0.89) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL13913968 | 0.84 | MAPT (0.89) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL13904925 | 0.81 | MAPT (0.83) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL19469440 | 0.80 | KMT2A (0.59) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6003816 | 0.80 | KMT2A (0.81) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL3716115 | 0.78 | MEN1 (0.77) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL3716116 | 0.78 | MEN1 (0.77) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL8861141 | 0.77 | MAPT (0.55) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017486-A | Cationic alpha-cyano-p-dimethylaminocinnamoyl dyes and paper dyed therewith | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-4017486-A | Cationic alpha-cyano-p-dimethylaminocinnamoyl dyes and paper dyed therewith | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | disclosed |