Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14141210 | 0.84 | TP53 (0.50) | HPGDTDP1EGFRERBB2BACE1 | |
| SCHEMBL11733364 | 0.81 | HDAC1 (0.36) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL2953707 | 0.74 | TPMT (0.53) | HPGDTDP1EGFRERBB2BACE1 | |
| SCHEMBL14541116 | 0.74 | MLYCD (0.45) | HPGDTDP1EGFRERBB2BACE1 | |
| SCHEMBL6139506 | 0.73 | MLYCD (0.44) | HPGDTDP1EGFRERBB2BACE1 | |
| Hydrochloric Acid SCHEMBL6172498 | 0.73 | TPMT (0.52) | HPGDTDP1EGFRERBB2BACE1 | |
| SCHEMBL3741746 | 0.73 | HPGD (0.67) | HDAC1HDAC6HPGDTDP1MLYCD | |
| SCHEMBL3900327 | 0.73 | CA12 (0.41) | HPGDTDP1EGFRERBB2MLYCD | |
| SCHEMBL13239446 | 0.72 | TPMT (0.50) | HPGDTDP1EGFRERBB2BACE1 | |
| SCHEMBL14376191 | 0.71 | HSD17B10 (0.47) | HPGDBACE1BACE2MLYCDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054576-A | Insect repellant compounds | STAUFFER CHEMICAL COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4028411-A | Insect repellent dimethylbenzamides | STAUFFER CHEMICAL COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-3966809-A | DIMETHYLBENZENE AMIDES | STAUFFER CHEMICAL COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3966806-A | DIMETHYLBENZENE AMIDES | STAUFFER CHEMICAL COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3960922-A | INSECT REPELLENTS | STAUFFER CHEMICAL COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
| US-3953477-A | INSECT REPELLENTS | STAUFFER CHEMICAL COMPANY (US) | 1976-04-27 | — | — | US | disclosed |