SCHEMBL11741990

SCHEMBL11741990

Cc1ccccc1C(=O)c1ccc([Si](C)(C)O[Si](C)(C)C)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 2/20 0.45
MAPK12 P53778 2/20 0.45
MAPK11 Q15759 2/20 0.45
MAPK14 Q16539 2/20 0.45
ALDH1A1 P00352 3/20 0.43
HTT P42858 1/20 0.43
AKR1C3 P42330 1/20 0.41
CHEK2 O96017 1/20 0.40
FFAR1 O14842 1/20 0.38
KMT2A Q03164 1/20 0.38
CSF1R P07333 1/20 0.38
SRD5A2 P31213 1/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ENPP3 O14638 1/20 0.37
ALPL P05186 1/20 0.37
XIAP P98170 1/20 0.37
LIG1 P18858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11749305 0.82 STS (0.52) ALDH1A1HTTCHEK2KMT2ANPC1
SCHEMBL11748559 0.82 MAPK13 (0.50) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL11742927 0.81 MAPT (0.54) ALDH1A1HTTAKR1C3KMT2ANPC1
SCHEMBL11778307 0.80 HPGD (0.52) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL9563138 0.79 ALDH1A1 (0.57) ALDH1A1HTTAKR1C3KMT2ASRD5A2
SCHEMBL11747506 0.78 ELANE (0.38) ALDH1A1AKR1C3CHEK2KMT2ANPC1
SCHEMBL11745663 0.75 CNR2 (0.46) MAPK13MAPK12MAPK11MAPK14L3MBTL1
SCHEMBL4543721 0.75 AKR1C3 (0.69) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL29530541 0.75 AKR1C3 (0.69) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL11750235 0.74 HPGD (0.51) HTTKMT2ASRD5A2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4042613-A PHOTOSENSITIZERS, POLYMERS DAI NIPPON PRINTING CO., LTD. (JA) 1977-08-16 US disclosed