SCHEMBL9563138

SCHEMBL9563138

Cc1ccc(C(=O)c2ccc([Si](C)(C)O[Si](C)(C)C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.57
LMNA P02545 2/20 0.57
SRD5A2 P31213 2/20 0.50
RAB9A P51151 4/20 0.42
HTT P42858 4/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 3/20 0.41
HPGD P15428 3/20 0.41
MAPT P10636 2/20 0.41
MITF O75030 1/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPK1 P28482 1/20 0.41
AKR1C3 P42330 1/20 0.40
PKM P14618 2/20 0.38
ATM Q13315 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
NLRP1 Q9C000 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13086261 0.84 ACHE (0.40) ALDH1A1LMNARAB9ATDP1SMN1; SMN2
SCHEMBL11746482 0.84 ALDH1A1 (0.47) ALDH1A1LMNASRD5A2RAB9AHTT
SCHEMBL11745663 0.84 CNR2 (0.46) TDP1SMN1; SMN2ATMCNR1CNR2
SCHEMBL11750235 0.84 HPGD (0.51) LMNASRD5A2HTTCES2CES1
SCHEMBL9563086 0.83 RXFP1 (0.54) ALDH1A1LMNARAB9AHTTCES2
SCHEMBL11740662 0.81 MAPT (0.61) ALDH1A1LMNARAB9AHTTTDP1
SCHEMBL11741990 0.79 MAPK13 (0.45) ALDH1A1SRD5A2RAB9AHTTNPC1
SCHEMBL9563126 0.79 ALDH1A1 (0.70) ALDH1A1LMNASRD5A2RAB9AHTT
SCHEMBL11745170 0.78 ELANE (0.35) ALDH1A1LMNARAB9AHTTSMN1; SMN2
SCHEMBL11749305 0.77 STS (0.52) ALDH1A1LMNARAB9AHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4042613-A PHOTOSENSITIZERS, POLYMERS DAI NIPPON PRINTING CO., LTD. (JA) 1977-08-16 US claimed
EP-0296878-B1 MODIFIED POLYSILOXANE-COATED SANITARY RUBBER ARTICLE AND PROCESS FOR ITS PRODUCTION DAIKYO GOMU SEIKO LTD. (JP) 1993-09-01 EP disclosed
US-5114794-A Coatings for medical equipment and drug containers for biological injections; adhesion; bonding strength DAIKYO GOMU SEIKO LTD. (JP) 1992-05-19 US disclosed
US-5110621-A Radiation with electrons, lasers, or ultraviolet rays to bond DAIKYO GOMU SEIKO LTD. (JP) 1992-05-05 US disclosed
EP-0296878-A2 Modified polysiloxane-coated sanitary rubber article and process for its production DAIKYO GOMU SEIKO LTD. (JP) 1988-12-28 EP disclosed
US-4042613-A PHOTOSENSITIZERS, POLYMERS DAI NIPPON PRINTING CO., LTD. (JA) 1977-08-16 US disclosed