Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.80 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flumequine SCHEMBL49830 | 0.89 | KDM4E (1.00) | KDM4ESMN1; SMN2CYP1A2PDE4APDE4B | |
| Flumequine SCHEMBL49829 | 0.89 | KDM4E (1.00) | KDM4ESMN1; SMN2CYP1A2PDE4APDE4B | |
| Flumequine SCHEMBL30767693 | 0.89 | KDM4E (1.00) | KDM4ESMN1; SMN2CYP1A2PDE4APDE4B | |
| Flumequine SCHEMBL29465201 | 0.89 | KDM4E (1.00) | KDM4ESMN1; SMN2CYP1A2PDE4APDE4B | |
| SCHEMBL11747062 | 0.88 | KDM4E (0.80) | KDM4ESMN1; SMN2CYP1A2PDE4APDE4B | |
| Flumequine SCHEMBL29024599 | 0.88 | KDM4E (0.98) | KDM4ESMN1; SMN2CYP1A2PDE4APDE4B | |
| Flumequine SCHEMBL29171109 | 0.88 | KDM4E (0.98) | KDM4ESMN1; SMN2CYP1A2PDE4APDE4B | |
| SCHEMBL11743280 | 0.87 | KDM4E (0.76) | KDM4ESMN1; SMN2CYP1A2PDE4APDE4B | |
| Water SCHEMBL11746655 | 0.87 | KDM4E (0.79) | KDM4ESMN1; SMN2CYP1A2PDE4APDE4B | |
| SCHEMBL11746236 | 0.86 | KDM4E (0.77) | KDM4ESMN1; SMN2CYP1A2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4014877-A | MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1977-03-29 | — | — | US | claimed |
| US-4014877-A | MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1977-03-29 | — | — | US | disclosed |
| US-4001243-A | ANTI-MICROBIAL | RIKER LABORATORIES, INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3985882-A | ADMISTERING | RIKER LABORATORIES, INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3969463-A | MICROBIOCIDE | RIKER LABORATORIES, INC. (US) | 1976-07-13 | — | — | US | disclosed |