Flumequine

Flumequine

SCHEMBL30767693

CC1CCc2cc(F)cc3c2n1c[13c]([13C](=O)O)[13c]3=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
CYP1A2 P05177 1/20 1.00
PDE4A P27815 1/20 0.61
PDE4B Q07343 1/20 0.61
PDE4C Q08493 1/20 0.61
PDE4D Q08499 1/20 0.61
LMNA P02545 1/20 0.57
HTR2A P28223 2/20 0.54
HTR2C P28335 2/20 0.54
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
ALB P02768 1/20 0.48
HRH3 Q9Y5N1 1/20 0.48
TUBB4A P04350 1/20 0.48
POLB P06746 1/20 0.48
TUBB P07437 1/20 0.48
TUBA3C P0DPH7 1/20 0.48
TUBA1B P68363 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flumequine SCHEMBL29465201 1.00 KDM4E (1.00) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Flumequine SCHEMBL49830 1.00 KDM4E (1.00) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Flumequine SCHEMBL49829 1.00 KDM4E (1.00) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Flumequine SCHEMBL29024599 0.99 KDM4E (0.98) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Flumequine SCHEMBL29171109 0.99 KDM4E (0.98) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Flumequine SCHEMBL27620591 0.92 KDM4E (0.84) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
SCHEMBL11742001 0.89 KDM4E (0.80) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
SCHEMBL11747062 0.89 KDM4E (0.80) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Flumequine SCHEMBL28121700 0.89 KDM4E (0.79) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Water SCHEMBL11746655 0.88 KDM4E (0.79) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250172532-A1 METHOD FOR DETECTING FOOD CONTAMINATION USING STABLE ISOTOPE-LABELED STANDARDS NASIRI, Azadeh (IR) 2025-05-29 US disclosed
WO-2024033723-A1 METHOD FOR DETECTING FOOD CONTAMINATION USING STABLE ISOTOPE-LABELED STANDARDS NASIRI AZADEH (IR) 2024-02-15 WO disclosed