Flumequine

Flumequine

SCHEMBL49829

CC1CCc2cc(F)cc3c(=O)c(C(=O)O)cn1c23

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
CYP1A2 P05177 1/20 1.00
PDE4A P27815 1/20 0.61
PDE4B Q07343 1/20 0.61
PDE4C Q08493 1/20 0.61
PDE4D Q08499 1/20 0.61
LMNA P02545 1/20 0.57
HTR2A P28223 2/20 0.54
HTR2C P28335 2/20 0.54
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
ALB P02768 1/20 0.48
HRH3 Q9Y5N1 1/20 0.48
TUBB4A P04350 1/20 0.48
POLB P06746 1/20 0.48
TUBB P07437 1/20 0.48
TUBA3C P0DPH7 1/20 0.48
TUBA1B P68363 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flumequine SCHEMBL29465201 1.00 KDM4E (1.00) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Flumequine SCHEMBL30767693 1.00 KDM4E (1.00) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Flumequine SCHEMBL49830 1.00 KDM4E (1.00) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Flumequine SCHEMBL29024599 0.99 KDM4E (0.98) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Flumequine SCHEMBL29171109 0.99 KDM4E (0.98) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Flumequine SCHEMBL27620591 0.92 KDM4E (0.84) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
SCHEMBL11742001 0.89 KDM4E (0.80) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
SCHEMBL11747062 0.89 KDM4E (0.80) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Flumequine SCHEMBL28121700 0.89 KDM4E (0.79) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B
Water SCHEMBL11746655 0.88 KDM4E (0.79) KDM4ESMN1; SMN2CYP1A2PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6934 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624057-B2 Bisphosphonate quinolone conjugates and uses thereof BIOVINC, LLC (US) 2026-05-12 US claimed
EP-4571306-A1 STABILIZING OXYGEN IN A COMPOSITION Instrumentation Laboratory Company (US) 2025-06-18 EP claimed
US-20250185632-A1 CONTINUOUS IN-SITU THERAPEUTIC TREATMENT SYSTEM FOR FISH IN FRESHWATER, FROM SEAWATER Salmoclinic Spa (CL) 2025-06-12 US claimed
US-20250189479-A1 STABILIZING OXYGEN IN A COMPOSITION INSTRUMENTATION LABORATORY COMPANY 2025-06-12 US claimed
US-20250172532-A1 METHOD FOR DETECTING FOOD CONTAMINATION USING STABLE ISOTOPE-LABELED STANDARDS NASIRI, Azadeh (IR) 2025-05-29 US claimed
CN-120005034-A Gold nanoflower immunochromatographic test strip for detecting flumequine and preparation method thereof 福建农林大学 2025-05-16 CN claimed
CN-119985873-A High-flux veterinary drug sensitivity testing device and method for aquatic products based on multilayer microfluidic chip 大连海事大学 2025-05-13 CN claimed
CN-119846127-A Method for rapidly detecting various antibiotics in environmental water body by on-line solid phase extraction-liquid chromatography-triple quadrupole mass spectrometry 昆明理工大学 2025-04-18 CN claimed
CN-119841958-A Nanometer antibody for broad-spectrum identification of quinolone medicines, and preparation method and application thereof 中国农业大学 2025-04-18 CN claimed
WO-2025080590-A1 CO-CRYSTALLIZATION OF ACTIVES WITH SACCHARIDE-BASED MOLECULAR FRAMEWORKS SCIENTIFIC HORIZONS CONSULTING LLC (US) 2025-04-17 WO claimed
EP-0310849-B1 Process for the synthesis of a benzo [ij] quinolizine-2-carboxylic acid derivative S P A SOCIETA' PRODOTTI ANTIBIOTICI S.p.a. (IT) 1993-03-03 EP claimed
WO-1992016209-A1 GRANULES AND VETERINARY COMPOSITIONS COMPRISING A WATER-SOLUBLE COMPLEX OF FLUMEQUINE REANAL FINOMVEGYSZERGYÁR (HU) 1992-10-01 WO claimed
EP-0470667-A1 Composition containing a 4-quinolone derivative complexed with a divalent metal ion LABORATOIRES MERCK, SHARP & DOHME-CHIBRET (FR) 1992-02-12 EP claimed
EP-0443381-A1 Effervescent composition, its production and use Takeda Chemical Industries, Ltd. (JP) 1991-08-28 EP claimed
EP-0412125-A1 PHARMACEUTICAL DOSAGE FORM FOR THE MEDICATION OF FISH. APOTHEKERNES LAB (NO) 1991-02-13 EP claimed
WO-1989012442-A1 PHARMACEUTICAL DOSAGE FORM FOR THE MEDICATION OF FISH APOTHEKERNES LABORATORIUM A.S (NO) 1989-12-28 WO claimed
EP-0310849-A1 Process for the synthesis of a benzo [ij] quinolizine-2-carboxylic acid derivative S P A SOCIETA' PRODOTTI ANTIBIOTICI S.p.a. (IT) 1989-04-12 EP claimed
US-4301289-A Process for 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-11-17 US claimed
US-4301288-A Process for 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-11-17 US claimed
US-3985882-A ADMISTERING RIKER LABORATORIES, INC. (US) 1976-10-12 US claimed