Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28941800 | 0.83 | ESR1 (0.55) | ESR1ESR2PTGS2RXRARXRB | |
| SCHEMBL1663207 | 0.83 | UGT2B7 (0.57) | UGT2B7 | |
| SCHEMBL10381408 | 0.83 | UGT2B7 (0.57) | UGT2B7 | |
| SCHEMBL29809804 | 0.83 | UGT2B7 (0.57) | UGT2B7 | |
| SCHEMBL10594958 | 0.82 | PTGS2 (0.53) | PTGS2 | |
| SCHEMBL7564603 | 0.81 | RXRA (0.49) | PTGS2RXRARXRBRXRGPTPN5 | |
| SCHEMBL11743708 | 0.81 | TYR (0.44) | PTGS2UGT2B7AKR1C3AKR1C2 | |
| SCHEMBL29594785 | 0.78 | UGT2B7 (0.43) | PTGS2UGT2B7AKR1C3AKR1C2 | |
| SCHEMBL11801547 | 0.77 | TYR (0.44) | PTGS2UGT2B7AKR1C3AKR1C2 | |
| SCHEMBL11802179 | 0.76 | CYP2A6 (0.52) | UGT2B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045485-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC AND ANTIPRURITIC ACTIVITY | SYNTEX CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-3960936-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, SKIN DISORDERS | SYNTEX CORPORATION (PM) | 1976-06-01 | — | — | US | disclosed |
| US-3947472-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (PM) | 1976-03-30 | — | — | US | disclosed |
| US-3935273-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |