Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL11745873

CCCOP(=O)(O)C(=O)NC.N

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.43
MMP3 P08254 3/20 0.43
MMP8 P22894 2/20 0.43
PLK1 P53350 1/20 0.40
MMP1 P03956 2/20 0.36
MMP9 P14780 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LPAR3 Q9UBY5 3/20 0.35
LPAR1 Q92633 2/20 0.35
LPAR2 Q9HBW0 2/20 0.35
SAT1 P21673 1/20 0.33
EPHX1 P07099 1/20 0.33
S1PR2 O95136 3/20 0.32
S1PR4 O95977 3/20 0.32
S1PR1 P21453 3/20 0.32
S1PR3 Q99500 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11742071 0.89 CYP3A4 (0.47) MMP2MMP3MMP8CA12CA1
Ammonia Solution, Strong SCHEMBL11744161 0.83 MMP2 (0.46) MMP2MMP3MMP8PLK1MMP1
SCHEMBL11738366 0.79 CA12 (0.47) MMP2MMP3MMP8PLK1MMP1
Trimethylammonium SCHEMBL11742304 0.76 MMP2 (0.43) MMP2MMP3MMP8MMP1MMP9
SCHEMBL11743281 0.74 MMP2 (0.38) MMP2MMP3MMP8PLK1MMP1
SCHEMBL4462228 0.71 LPAR3 (0.38) ALDH1A1LPAR3LPAR1LPAR2
Ammonia Solution, Strong SCHEMBL128358 0.71 LPAR3 (0.44) ALDH1A1LPAR3LPAR1LPAR2
Ammonia Solution, Strong SCHEMBL28426122 0.71 LPAR3 (0.44) ALDH1A1LPAR3LPAR1LPAR2
Propyl Phosphate SCHEMBL10354165 0.71
Propyl Phosphate SCHEMBL11529608 0.71 LPAR3 (0.62) LPAR3LPAR1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4048156-A PLANT GROWTH REGULATORS E. I DU PONT DE NEMOURS AND COMPANY (US) 1977-09-13 US disclosed
US-3997544-A Plant growth regulant carbamoylphosphonates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-12-14 US disclosed
US-3981870-A Plant growth regulant carbamoylphosphonates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-09-21 US disclosed
US-3975464-A PLANT GROWTH REGULATOR E. I. DUPONT DE NEMOURS AND COMPANY (US) 1976-08-17 US disclosed
US-3952074-A PLANT GROWTH REGULATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-20 US disclosed