SCHEMBL11738366

SCHEMBL11738366

CCCOP(=O)(OCCC)C(=O)NC

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
MMP2 P08253 4/20 0.41
MMP3 P08254 3/20 0.41
MMP8 P22894 2/20 0.41
ALDH1A1 P00352 1/20 0.41
PLK1 P53350 1/20 0.38
EPHX1 P07099 1/20 0.35
MMP1 P03956 2/20 0.34
MMP9 P14780 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LPAR3 Q9UBY5 3/20 0.33
LPAR1 Q92633 2/20 0.33
LPAR2 Q9HBW0 2/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11742952 0.82 CA12 (0.61) CA12CA1CA2CA9MMP2
Ammonia Solution, Strong SCHEMBL11745873 0.79 MMP2 (0.43) CA12CA1CA2CA9MMP2
SCHEMBL11743281 0.78 MMP2 (0.38) CA12CA1CA2CA9MMP2
SCHEMBL2242980 0.76 ALDH1A1 (0.41) CA12CA1CA2CA9MMP2
SCHEMBL2983513 0.75 ALDH1A1 (0.40) CA12CA1CA2CA9ALDH1A1
SCHEMBL18166783 0.75 ALDH1A1 (0.44) CA12CA1CA2CA9ALDH1A1
SCHEMBL2987740 0.73 ALDH1A1 (0.39) CA12CA1CA2CA9ALDH1A1
SCHEMBL2239225 0.71 ALDH1A1 (0.38) CA12CA1CA2CA9ALDH1A1
SCHEMBL2978635 0.71 ALDH1A1 (0.38) CA12CA1CA2CA9ALDH1A1
SCHEMBL10395318 0.70 MEN1 (0.38) CA12CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4048156-A PLANT GROWTH REGULATORS E. I DU PONT DE NEMOURS AND COMPANY (US) 1977-09-13 US disclosed
US-3997544-A Plant growth regulant carbamoylphosphonates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-12-14 US disclosed
US-3981870-A Plant growth regulant carbamoylphosphonates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-09-21 US disclosed
US-3975464-A PLANT GROWTH REGULATOR E. I. DUPONT DE NEMOURS AND COMPANY (US) 1976-08-17 US disclosed
US-3952074-A PLANT GROWTH REGULATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-20 US disclosed