Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745901 | 1.00 | TSHR (0.54) | TSHRALDH1A1HPGDTDP1MAPT | |
| SCHEMBL731102 | 0.85 | MCOLN3 (0.60) | TSHRALDH1A1HPGDTDP1NSD2 | |
| SCHEMBL9568275 | 0.84 | MCOLN3 (0.59) | TSHRALDH1A1HPGDTDP1NSD2 | |
| Hydrochloric Acid SCHEMBL28777156 | 0.84 | MCOLN3 (0.59) | TSHRALDH1A1HPGDTDP1NSD2 | |
| SCHEMBL9568274 | 0.84 | MCOLN3 (0.59) | TSHRALDH1A1HPGDTDP1NSD2 | |
| SCHEMBL6516381 | 0.83 | MAPT (0.53) | TSHRALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL28110935 | 0.83 | SMN1; SMN2 (0.52) | TSHRALDH1A1HPGDTDP1MAPT | |
| SCHEMBL392626 | 0.82 | HPGD (0.62) | TSHRALDH1A1HPGDTDP1NSD2 | |
| SCHEMBL1828638 | 0.81 | MAPT (0.51) | TSHRALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL10423505 | 0.81 | ALDH1A1 (0.60) | TSHRALDH1A1HPGDTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4063889-A | Halosolvent dyeing process for polyester with cationic dyes having sulfosuccinate anions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-12-20 | — | — | US | claimed |
| US-9206125-B2 | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |
| US-9206125-B2 | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |
| US-9206125-B2 | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |
| US-20130203738-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | NAGOYA CITY UNIVERSITY (JP) | 2013-08-08 | — | — | US | disclosed |
| US-20130203738-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | NAGOYA CITY UNIVERSITY (JP) | 2013-08-08 | — | — | US | disclosed |
| US-20130203738-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | NAGOYA CITY UNIVERSITY (JP) | 2013-08-08 | — | — | US | disclosed |
| EP-2535059-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | Public University Corporation Yokohama City University (JP) | 2012-12-19 | — | — | EP | disclosed |
| EP-2535059-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | Public University Corporation Yokohama City University (JP) | 2012-12-19 | — | — | EP | disclosed |
| US-4063889-A | Halosolvent dyeing process for polyester with cationic dyes having sulfosuccinate anions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203738-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | RCOR1, MSI2, RCOR3 | TSHR 2959/4885ALDH1A1 2604/4885HPGD 3352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.