Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568275 | 0.98 | MCOLN3 (0.59) | MCOLN3CRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL9568274 | 0.98 | MCOLN3 (0.59) | MCOLN3CRHBPCRHR2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL28777156 | 0.98 | MCOLN3 (0.59) | MCOLN3CRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL11745892 | 0.85 | TSHR (0.54) | MCOLN3CRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL11745901 | 0.85 | TSHR (0.54) | MCOLN3CRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL10744526 | 0.84 | MCOLN3 (0.50) | MCOLN3CRHBPCRHR2ALDH1A1HPGD | |
| Hydrogen Peroxide SCHEMBL28682950 | 0.84 | TSHR (0.57) | MCOLN3CRHBPCRHR2ALDH1A1TDP1 | |
| SCHEMBL29397077 | 0.83 | MCOLN3 (0.58) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL10700954 | 0.83 | MCOLN3 (0.58) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL994972 | 0.83 | MCOLN3 (0.58) | MCOLN3CRHBPCRHR2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102491906-B | Synthetic method for 2-methyl-3-trifluoromethyl phenylamine | QILU ANIMAL HEALTH PRODUCTS CO | 2013-10-23 | — | — | CN | claimed |
| CN-102491906-A | Synthetic method for 2-methyl-3-trifluoromethyl phenylamine | QILU ANIMAL HEALTH PRODUCTS CO | 2012-06-13 | — | — | CN | claimed |
| WO-2010099518-A2 | METHOD FOR MANUFACTURE OF 2-OXOIMIDAZOLIDINES | THESIS CHEMISTRY, LLC (US) | 2010-09-02 | — | — | WO | claimed |
| EP-1548069-B1 | Liquid formulations of direct dyes | BASF SE (DE) | 2010-08-04 | — | — | EP | claimed |
| US-7331998-B2 | Liquid formulations of direct dyes | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-19 | — | — | US | claimed |
| CN-100334255-C | Method for applying a phosphate covering and use of metal parts thus phospated | CHEMETALL GMBH (DE) | 2007-08-29 | — | — | CN | claimed |
| US-20050132510-A1 | Liquid formulations of direct dyes | BASF AKIENGESELLSCHAFT (DE) | 2005-06-23 | — | — | US | claimed |
| CN-1196669-C | Method for producing substituted nitro benzoic acids by oxidation of corresponding nitro toluenes, nitro benzyl alcohols, esters and/or ethers | BAYER AG (DE) | 2005-04-13 | — | — | CN | claimed |
| EP-1274672-B1 | METHOD FOR PRODUCING SUBSTITUTED NITRO BENZOIC ACIDS BY OXIDATION OF CORRESPONDING NITRO TOLUENES, NITRO BENZYL ALCOHOLS, ESTERS AND/OR ETHERS | BAYER CHEMICALS AG (DE) | 2004-03-03 | — | — | EP | claimed |
| US-20040039227-A1 | Method for producing substituted nitro benzoic acids by oxidation of corresponding nitro toluenes, nitrol benzyl alcohols, esters and/or ethers | LANXESS DEUTSCHLAND GMBH (DE) | 2004-02-26 | — | — | US | claimed |
| EP-1016405-A2 | Arylating medicaments | Radopath Pharmaceuticals International Limited (GB) | 2000-07-05 | — | — | EP | claimed |
| CN-1203886-A | Method for producing hydrogen sulfide | TANG PEISI (CN) | 1999-01-06 | — | — | CN | claimed |
| EP-0700287-A1 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1996-03-13 | — | — | EP | claimed |
| EP-0460544-B1 | Process for the preparation of sulphonated anthranilic acids | BASF AG (DE) | 1995-08-09 | — | — | EP | claimed |
| WO-1994027584-A2 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1994-12-08 | — | — | WO | claimed |
| EP-0380067-B1 | IMPROVED METHOD OF LUBRICATING IRON AND STEEL BEFORE COLD WORKING | HENKEL CORPORATION (US) | 1993-05-26 | — | — | EP | claimed |
| US-5196573-A | Process for the preparation of sulfonated anthranilic acids | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | claimed |
| US-5086128-A | HIGH MOLECULAR WEIGHT ARYLENE SULPHIDE POLYMER MELT MIXED WITH AROMATIC NITRO COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | claimed |
| EP-0380067-A1 | Improved method of lubricating iron and steel before cold working | HENKEL CORPORATION (US) | 1990-08-01 | — | — | EP | claimed |
| US-4426291-A | Solvent extraction of nitrated organic compounds from aqueous solutions | BASF WYANDOTTE CORPORATION (US) | 1984-01-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039227-A1 | Method for producing substituted nitro benzoic acids by oxidation of corresponding nitro toluenes, nitrol benzyl alcohols, esters and/or ethers | NOS2, NOS1, CYP2E1 | MCOLN3 3645/4885CRHBP 2926/4885CRHR2 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.