Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 13/20 | 0.35 |
| ▸ | WNT3A | P56704 | 12/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11752377 | 0.96 | CTNNB1 (0.36) | CTNNB1WNT3AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL11801328 | 0.86 | CTNNB1 (0.41) | CTNNB1WNT3APTGER2ALDH1A1TP53 | |
| SCHEMBL11731631 | 0.83 | CTNNB1 (0.40) | CTNNB1WNT3AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL11753584 | 0.83 | ALDH1A1 (0.40) | CTNNB1WNT3AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11733551 | 0.82 | CTNNB1 (0.42) | CTNNB1WNT3AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL6836837 | 0.76 | CTNNB1 (0.43) | CTNNB1WNT3AALDH1A1HPGDPKM | |
| SCHEMBL11753618 | 0.75 | KDM4E (0.36) | MAPTL3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL4857484 | 0.72 | CTNNB1 (0.56) | CTNNB1WNT3AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL11750545 | 0.72 | ALDH1A1 (0.49) | CTNNB1WNT3AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11747287 | 0.71 | CTNNB1 (0.39) | CTNNB1WNT3AALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041165-A | TREATING DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3937833-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |