Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677514 | 0.78 | MAPT (0.53) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL11678805 | 0.76 | L3MBTL1 (0.54) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL11746256 | 0.75 | CTNNB1 (0.35) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL11677470 | 0.72 | RAB9A (0.53) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL11752377 | 0.71 | CTNNB1 (0.36) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL11753611 | 0.70 | S1PR5 (0.36) | NPC1HDAC1 | |
| SCHEMBL5328213 | 0.66 | CTNNB1 (0.57) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL10008853 | 0.65 | HSD17B3 (0.57) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL11679519 | 0.65 | MAPT (0.49) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL11797647 | 0.65 | HPGD (0.41) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041165-A | TREATING DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3937833-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |