Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11744476 | 0.83 | TDP1 (0.64) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL4283513 | 0.81 | KMT2A (0.54) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL4283506 | 0.81 | KMT2A (0.54) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL11130914 | 0.81 | KMT2A (0.78) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL11287057 | 0.81 | KMT2A (0.78) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL11446063 | 0.80 | TDP1 (0.46) | MEN1KMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL11446062 | 0.80 | TDP1 (0.46) | MEN1KMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL11465026 | 0.80 | MAPT (0.55) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL11465027 | 0.80 | MAPT (0.55) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL1444740 | 0.79 | ALDH1A1 (0.66) | MEN1KMT2ATDP1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4062836-A | YELLOW | CIBA-GEIGY CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |
| US-3943120-A | WATER INSOLUBLE | CIBA-GEIGY AG (CH) | 1976-03-09 | — | — | US | disclosed |