Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534725 | 0.99 | CHEK1 (0.51) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11745480 | 0.83 | CHEK1 (0.60) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11744815 | 0.77 | CHEK1 (0.60) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| Hydrochloric Acid SCHEMBL11744919 | 0.75 | RECQL (0.56) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11536976 | 0.72 | CHEK1 (0.66) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11744763 | 0.71 | RECQL (0.74) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11747499 | 0.71 | CHEK1 (0.53) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11747039 | 0.71 | CHEK1 (0.60) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11747298 | 0.71 | CHEK1 (0.55) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11746758 | 0.71 | RECQL (0.69) | CHEK1PDGFRACDK5DYRK1ALRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064261-A | TRIAZOLOBENOXAZOLE, TRIAZOLOBENZOTHIAZOLE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |