Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11747039 | 0.83 | CHEK1 (0.60) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11745480 | 0.76 | CHEK1 (0.60) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11536976 | 0.74 | CHEK1 (0.66) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11746758 | 0.73 | RECQL (0.69) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| Hydrochloric Acid SCHEMBL11747896 | 0.72 | CHEK1 (0.64) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11747499 | 0.71 | CHEK1 (0.53) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11744763 | 0.71 | RECQL (0.74) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11746654 | 0.71 | CHEK1 (0.53) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| SCHEMBL11746931 | 0.70 | CHEK1 (0.66) | CHEK1PDGFRACDK5DYRK1ALRRK2 | |
| Bromide SCHEMBL11743370 | 0.70 | CHEK1 (0.96) | CHEK1PDGFRACDK5DYRK1ALRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064261-A | TRIAZOLOBENOXAZOLE, TRIAZOLOBENZOTHIAZOLE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |