Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748107 | 0.79 | RAB9A (0.54) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL9215294 | 0.74 | PRKD3 (0.38) | ESR1ESR2CYP11B2MAPTRAB9A | |
| SCHEMBL11751464 | 0.72 | CHEK1 (0.45) | CYP11B2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9172793 | 0.72 | MAPT (0.44) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL11743631 | 0.71 | RAB9A (0.55) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL11744578 | 0.71 | MAPT (0.48) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL11780492 | 0.71 | MEN1 (0.41) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL9172808 | 0.70 | MAPT (0.39) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL10498384 | 0.68 | CYP1A2 (0.45) | ESR1ESR2MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL26153496 | 0.66 | CYP1A2 (0.58) | ESR1ESR2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021556-A | PYRAZOLO(1,5A) PYRIMIDINE DERIVATIVES | ICN PHARMACEUTICALS, INC. (US) | 1977-05-03 | — | — | US | disclosed |