Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11741491 | 0.96 | MEN1 (0.33) | TSHR | |
| SCHEMBL11737742 | 0.92 | TSHR (0.41) | TSHR | |
| SCHEMBL11737703 | 0.88 | TSHR (0.41) | TSHR | |
| SCHEMBL11742126 | 0.87 | — | — | |
| SCHEMBL11743702 | 0.85 | ALDH1A1 (0.32) | TSHR | |
| SCHEMBL6569485 | 0.83 | TSHR (0.41) | TSHR | |
| SCHEMBL27787472 | 0.83 | TSHR (0.38) | TSHR | |
| SCHEMBL129087 | 0.82 | TSHR (0.40) | TSHR | |
| SCHEMBL106941 | 0.82 | TSHR (0.30) | TSHR | |
| SCHEMBL10846961 | 0.81 | ALDH1A1 (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029842-A | POLYMETHYL METHACRYLATE COATED AND OVERCOATED WITH TRIALKOXYSILANES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) | 1977-06-14 | — | — | US | disclosed |