Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11737742 | 0.92 | TSHR (0.41) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL11737703 | 0.92 | TSHR (0.41) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL11742126 | 0.87 | — | — | |
| SCHEMBL129087 | 0.87 | TSHR (0.40) | TSHRCYP3A4HPGDALDH1A1ADRB2 | |
| SCHEMBL20394649 | 0.85 | TSHR (0.39) | TSHRCYP3A4HPGDALDH1A1ADRB2 | |
| SCHEMBL11739768 | 0.83 | TSHR (0.37) | TSHRCYP3A4HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11747465 | 0.83 | TSHR (0.32) | TSHR | |
| SCHEMBL11741491 | 0.83 | MEN1 (0.33) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL27787472 | 0.83 | TSHR (0.38) | TSHRCYP3A4HPGDALDH1A1ADRB2 | |
| SCHEMBL931900 | 0.81 | TSHR (0.36) | TSHRHPGDALDH1A1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640630-B1 | Aquous dispersion of plastics modified with silicium for the preparation of adhesives | POLYMER LATEX GMBH & CO KG (DE) | 1998-08-12 | — | — | EP | claimed |
| EP-0640630-A1 | Aquous dispersion of plastics modified with silicium for the preparation of adhesives | HÜLS AKTIENGESELLSCHAFT (DE) | 1995-03-01 | — | — | EP | claimed |
| EP-1408057-A1 | Universal binder for structural applications | Polymer Latex GmbH & Co. KG (DE) | 2004-04-14 | — | — | EP | disclosed |
| EP-0640630-B1 | Aquous dispersion of plastics modified with silicium for the preparation of adhesives | POLYMER LATEX GMBH & CO KG (DE) | 1998-08-12 | — | — | EP | disclosed |
| US-4029842-A | POLYMETHYL METHACRYLATE COATED AND OVERCOATED WITH TRIALKOXYSILANES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) | 1977-06-14 | — | — | US | disclosed |