Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 6/20 | 0.44 |
| ▸ | RXRB | P28702 | 6/20 | 0.44 |
| ▸ | RXRG | P48443 | 6/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755719 | 1.00 | KMT2A (0.54) | KMT2AMEN1NR4A2KIF11RXRA | |
| SCHEMBL11749070 | 0.94 | MEN1 (0.44) | KMT2AMEN1NR4A2KIF11RXRA | |
| SCHEMBL11751391 | 0.87 | STAT3 (0.42) | KMT2AMEN1KIF11RXRARXRB | |
| SCHEMBL11753479 | 0.87 | STAT3 (0.42) | KMT2AMEN1KIF11RXRARXRB | |
| SCHEMBL2744315 | 0.85 | NR4A2 (0.60) | KMT2ANR4A2RXRARXRBRXRG | |
| SCHEMBL11749827 | 0.83 | CYP2C19 (0.51) | KMT2ANR4A2RXRARXRBRXRG | |
| SCHEMBL11752646 | 0.83 | CYP2C19 (0.51) | KMT2ANR4A2RXRARXRBRXRG | |
| SCHEMBL11749503 | 0.82 | MEN1 (0.54) | KMT2AMEN1NR4A2KIF11RXRA | |
| SCHEMBL29154647 | 0.82 | MAPK13 (0.68) | KMT2AMEN1NR4A2KIF11RXRA | |
| SCHEMBL11752547 | 0.82 | MEN1 (0.54) | KMT2AMEN1NR4A2KIF11RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |