Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.68 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.68 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.68 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 4/20 | 0.45 |
| ▸ | RXRB | P28702 | 4/20 | 0.45 |
| ▸ | RXRG | P48443 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091239 | 0.85 | MAPK13 (0.83) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL11749503 | 0.82 | MEN1 (0.54) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL11747487 | 0.82 | KMT2A (0.54) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL11755719 | 0.82 | KMT2A (0.54) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL11752547 | 0.82 | MEN1 (0.54) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL1387446 | 0.81 | MAPK14 (1.00) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL29154643 | 0.80 | MAPK13 (0.69) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL29154645 | 0.80 | MAPK13 (0.69) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL13772755 | 0.80 | MAPK13 (0.69) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL28889445 | 0.79 | PTGS2 (0.50) | MAPK13MAPK12MAPK11MAPK14PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510430-B | Oxazole compound and synthetic method and application thereof | 南昌大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-117510430-A | Oxazole compound and synthetic method and application thereof | 南昌大学 | 2024-02-06 | — | — | CN | disclosed |