Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 4/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11747487 | 0.94 | KMT2A (0.54) | MEN1KMT2AKIF11NR4A2MAPK14 | |
| SCHEMBL11755719 | 0.94 | KMT2A (0.54) | MEN1KMT2AKIF11NR4A2MAPK14 | |
| SCHEMBL11751391 | 0.92 | STAT3 (0.42) | MEN1KMT2AKIF11RXRARXRB | |
| SCHEMBL11753479 | 0.92 | STAT3 (0.42) | MEN1KMT2AKIF11RXRARXRB | |
| SCHEMBL11753859 | 0.83 | NPC1 (0.40) | KMT2AKIF11NR4A2NOTUMMAPK14 | |
| SCHEMBL11755256 | 0.80 | MAPK14 (0.50) | NR4A2MAPK14 | |
| SCHEMBL11755633 | 0.79 | MEN1 (0.44) | MEN1KMT2AKIF11NR4A2MKNK1 | |
| SCHEMBL11749410 | 0.77 | NR4A2 (0.47) | MEN1KMT2ANR4A2MAPK14GFER | |
| SCHEMBL11755115 | 0.77 | RXRA (0.46) | MEN1KMT2ANR4A2MAPK14RXRA | |
| SCHEMBL11751140 | 0.77 | KMT2A (0.40) | MEN1KMT2ANR4A2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |