SCHEMBL1174774

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15247939	0.84	GAA (0.42)	PIK3CDTSHRALDH1A1SMN1; SMN2CYP1A2
	SCHEMBL1174384	0.83	PIN1 (0.49)	PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG
	SCHEMBL1174295	0.80	HTR4 (0.49)	CYP3A4GAA
	SCHEMBL1175453	0.79	CNR2 (0.46)	TP53MAPTALDH1A1CYP1A2CYP2C9
	SCHEMBL1175186	0.78	CNR2 (0.52)	TP53MAPTALDH1A1CYP1A2CYP3A4
	SCHEMBL1176158	0.78	CNR2 (0.47)	ALDH1A1NPC1GAAPOLB
	SCHEMBL1176161	0.78	CNR2 (0.47)	ALDH1A1NPC1GAAPOLB
	SCHEMBL1175787	0.78	CNR2 (0.45)	CNR1TP53ALDH1A1HTR2CCYP1A2
	SCHEMBL1174726	0.78	CNR2 (0.52)	TP53MAPTALDH1A1CYP1A2CYP3A4
	SCHEMBL1174725	0.78	CNR2 (0.52)	TP53MAPTALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.