Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751988 | 0.82 | SIGMAR1 (0.54) | SIGMAR1HRH1HRH3DRD2SLC6A4 | |
| SCHEMBL11748974 | 0.80 | SIGMAR1 (0.54) | SIGMAR1HRH1HRH3DRD2SLC6A4 | |
| SCHEMBL11865232 | 0.78 | SIGMAR1 (0.53) | SIGMAR1HRH1HRH3DRD2SLC6A4 | |
| SCHEMBL11551109 | 0.76 | SIGMAR1 (0.56) | SIGMAR1HRH1HRH3DRD2SLC6A4 | |
| SCHEMBL11747299 | 0.75 | IGF1R (0.32) | — | |
| SCHEMBL11748266 | 0.74 | KDM4E (0.55) | HRH3 | |
| SCHEMBL19904622 | 0.74 | HRH1 (0.53) | SIGMAR1HRH1HRH3DRD2SLC6A4 | |
| SCHEMBL7996805 | 0.74 | HRH1 (0.53) | SIGMAR1HRH1DRD2SLC6A4SLC6A3 | |
| SCHEMBL11751266 | 0.72 | MAOB (0.60) | SIGMAR1HRH1HRH3BCHEACHE | |
| SCHEMBL11680152 | 0.71 | SIGMAR1 (0.58) | SIGMAR1HRH1HRH3DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041165-A | TREATING DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3937833-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |