Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11678798 | 0.98 | SIGMAR1 (0.56) | SIGMAR1HRH1KDM4EL3MBTL1HRH3 | |
| SCHEMBL11782472 | 0.98 | HRH1 (0.58) | SIGMAR1HRH1KDM4EL3MBTL1HRH3 | |
| SCHEMBL11678845 | 0.85 | NPC1 (0.57) | SIGMAR1 | |
| SCHEMBL11748974 | 0.84 | SIGMAR1 (0.54) | SIGMAR1HRH1HRH3DRD2SLC6A4 | |
| SCHEMBL11751988 | 0.84 | SIGMAR1 (0.54) | SIGMAR1HRH1HRH3DRD2SLC6A4 | |
| SCHEMBL11679286 | 0.83 | SIGMAR1 (0.62) | SIGMAR1HRH3ACHE | |
| SCHEMBL11865232 | 0.82 | SIGMAR1 (0.53) | SIGMAR1HRH1HRH3DRD2SLC6A4 | |
| SCHEMBL11677731 | 0.79 | HTT (0.39) | SIGMAR1DRD2SLC6A4 | |
| SCHEMBL11637536 | 0.78 | GRIN2B (0.55) | SIGMAR1HRH1HRH3DRD2SLC6A4 | |
| SCHEMBL11677886 | 0.78 | SIGMAR1 (0.70) | SIGMAR1HRH3SLC6A4GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |