Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524250 | 0.85 | MTNR1A (0.57) | MEN1MAPTKMT2AMTNR1ANLN | |
| SCHEMBL9172150 | 0.83 | MTNR1A (0.55) | MEN1MAPTKMT2AMTNR1ANLN | |
| SCHEMBL30496750 | 0.80 | MTNR1A (0.58) | MEN1MAPTKMT2AMTNR1ANLN | |
| SCHEMBL4100261 | 0.80 | MTNR1A (0.58) | MEN1MAPTKMT2AMTNR1ANLN | |
| SCHEMBL29145305 | 0.79 | MTNR1A (0.62) | MEN1MAPTKMT2AMTNR1ACHRNB2 | |
| SCHEMBL1305042 | 0.78 | MEN1 (0.58) | MEN1MAPTKMT2AMTNR1ACHRNB2 | |
| Hydrochloric Acid SCHEMBL28128851 | 0.78 | MTNR1A (0.57) | MEN1MAPTKMT2AMTNR1ANLN | |
| SCHEMBL1386337 | 0.78 | MTNR1A (0.76) | MEN1MAPTKMT2AMTNR1ACHRNB2 | |
| SCHEMBL22323341 | 0.78 | MEN1 (0.66) | MEN1MAPTKMT2AMTNR1ACHRNB2 | |
| SCHEMBL22444396 | 0.77 | ALOX12 (0.63) | MEN1MAPTKMT2ACA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009279-A | 2-IMINO-1,3-DITHIETANES | AMERICAN CYANAMID COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
| US-3997668-A | INSECTICIDES, MITICIDE | AMERICAN CYANAMID COMPANY (US) | 1976-12-14 | — | — | US | disclosed |
| US-3975528-A | Insecticidal 2-imino-1,3-dithietane derivatives | AMERICAN CYANAMID COMPANY (US) | 1976-08-17 | — | — | US | disclosed |