Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28718019 | 0.83 | CES2 (0.50) | ALDH1A1CES2CES1SMN1; SMN2NPC1 | |
| SCHEMBL14451127 | 0.82 | CA12 (0.57) | ALDH1A1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL11868608 | 0.82 | TDP1 (0.57) | ALDH1A1CES2CES1SMN1; SMN2NPC1 | |
| SCHEMBL11743861 | 0.80 | CES2 (0.46) | ALDH1A1CES2CES1SMN1; SMN2NPC1 | |
| SCHEMBL8519997 | 0.80 | LMNA (0.53) | ALDH1A1NPC1RAB9ATSHRGAA | |
| SCHEMBL1020413 | 0.79 | TSHR (0.56) | ALDH1A1CES2CES1SMN1; SMN2L3MBTL1 | |
| SCHEMBL12673729 | 0.78 | CA1 (0.62) | CES2CES1SMN1; SMN2CA1CA2 | |
| SCHEMBL11751167 | 0.78 | PARP1 (0.50) | ALDH1A1RAB9AL3MBTL1ALOX15HPGD | |
| SCHEMBL27668297 | 0.78 | TSHR (0.54) | ALDH1A1CES2CES1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27647867 | 0.78 | TSHR (0.54) | ALDH1A1CES2CES1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008271-A | Process for preparing a mixed anhydride of a sulfonic acid and a carboxylic acid | ETHYL CORPORATION (US) | 1977-02-15 | — | — | US | disclosed |