Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 7/20 | 0.34 |
| ▸ | CA2 | P00918 | 7/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.34 |
| ▸ | CA9 | Q16790 | 6/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511717 | 0.91 | ADRB2 (0.36) | TSHRCA1CA2 | |
| SCHEMBL26106906 | 0.78 | LPAR3 (0.43) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL11791100 | 0.78 | LPAR3 (0.43) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL11747425 | 0.78 | CES1 (0.41) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL24829886 | 0.75 | THRB (0.44) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL4505591 | 0.75 | THRB (0.44) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL278721 | 0.75 | THRB (0.44) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL16311961 | 0.75 | THRB (0.44) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL127022 | 0.75 | THRB (0.44) | TSHRTHRBMEN1HTTKMT2A | |
| SCHEMBL16311963 | 0.75 | THRB (0.44) | TSHRTHRBMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049748-A | CHEMICAL RESISTANCE | CHATTEM DRUG & CHEMICAL COMPANY (US) | 1977-09-20 | — | — | US | disclosed |