SCHEMBL11748932

SCHEMBL11748932

CCCCC(C)(C)C1Nc2ccccc2N1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR5A P47898 2/20 0.36
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GAA P10253 3/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
GFER P55789 1/20 0.34
KMT2A Q03164 1/20 0.34
CREBBP Q92793 2/20 0.33
BRD4 O60885 1/20 0.33
BRPF1 P55201 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
NOS2 P35228 1/20 0.31
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11749109 0.93 CNR2 (0.34) HTR5AALDH1A1KDM4EHSD17B10GAA
SCHEMBL11751614 0.82 HTR5A (0.34) HTR5AALDH1A1KDM4EHSD17B10GAA
SCHEMBL11750901 0.80 GAA (0.38) HTR5AKDM4EGAAMEN1MAPT
SCHEMBL11748558 0.77 MEN1 (0.36) HTR5AALDH1A1KDM4EHSD17B10GAA
SCHEMBL11753669 0.71 CREBBP (0.40) HTR5AALDH1A1KDM4EGAAMEN1
SCHEMBL18771462 0.67 KDM4E (0.33) HTR5AALDH1A1KDM4EHSD17B10GAA
SCHEMBL13956010 0.64 BCHE (0.34) MEN1MAPTKMT2AESR1ESR2
SCHEMBL21891360 0.64 MEN1 (0.42) ALDH1A1HSD17B10MEN1KMT2AHPGD
SCHEMBL13892507 0.63 MEN1 (0.37) GAAMEN1MAPTALOX15CASP1
SCHEMBL4533080 0.62 CREBBP (0.35) HTR5AALDH1A1GAAMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873350-B2 Dissolution of oxidized cellulose COVIDIEN LP (US) 2024-01-16 US disclosed
US-11872244-B2 Thixotropic oxidized cellulose solutions and medical applications thereof COVIDIEN LP (US) 2024-01-16 US disclosed
EP-3085396-B1 RESORBABLE OXIDIZED CELLULOSE EMBOLIZATION SOLUTION COVIDIEN LP (US) 2022-07-20 EP disclosed
US-20210238314-A1 DISSOLUTION OF OXIDIZED CELLULOSE COVIDIEN LP 2021-08-05 US disclosed
US-11065204-B2 Oxidized cellulose microspheres COVIDIEN LP (US) 2021-07-20 US disclosed
US-11053323-B2 Dissolution of oxidized cellulose and particle preparation by cross-linking with multivalent cations COVIDIEN LP (US) 2021-07-06 US disclosed
EP-3103442-B1 MICROSPHERES INCLUDING OXIDIZED CELLULOSE COVIDIEN LP (US) 2021-05-12 EP disclosed
US-10982012-B2 Dissolution of oxidized cellulose COVIDIEN LP (US) 2021-04-20 US disclosed
EP-3111928-B1 MICROSPHERES INCLUDING OXIDIZED CELLULOSE COVIDIEN LP (US) 2020-12-23 EP disclosed
US-10584184-B2 Medical devices based on oxidized cellulose COVIDIEN LP (US) 2020-03-10 US disclosed
CN-103524761-A Medical devices based on cellulose COVIDIEN LP 2014-01-22 CN disclosed
US-20140005376-A1 Dissolution of Oxidized Cellulose and Particle Preparation by Solvent and Non-Solvent Precipitation COVIDIEN LP (US) 2014-01-02 US disclosed
US-20140005377-A1 Dissolution of Oxidized Cellulose and Particle Preparation by Dispersion and Neutralization COVIDIEN LP (US) 2014-01-02 US disclosed
US-20140005378-A1 Dissolution of Oxidized Cellulose and Particle Preparation by Cross-Linking With Multivalent Cations COVIDIEN LP (US) 2014-01-02 US disclosed
US-20140005375-A1 Medical Devices Based On Oxidized Cellulose COVIDIEN LP (US) 2014-01-02 US disclosed
US-20130323312-A1 Microspheres Including Oxidized Cellulose CONFLUENT SURGICAL, INC. (US) 2013-12-05 US disclosed
US-20130323315-A1 Microspheres Including Oxidized Cellulose CONFLUENT SURGICAL, INC. (US) 2013-12-05 US disclosed
EP-2668943-A1 Microspheres including oxidized cellulose Confluent Surgical, Inc. (US) 2013-12-04 EP disclosed
EP-2668942-A1 Microspheres including oxidized cellulose Confluent Surgical, Inc. (US) 2013-12-04 EP disclosed
US-4016113-A AROMATIC AND ALKYL SUBSTITUTED AROMATIC ORTHO DIAMINES OLIN CORPORATION (US) 1977-04-05 US disclosed