SCHEMBL11748558

SCHEMBL11748558

CCCC(C)(CCC)C1Nc2ccccc2N1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
GFER P55789 1/20 0.36
KMT2A Q03164 1/20 0.36
CREBBP Q92793 4/20 0.35
BRD4 O60885 4/20 0.35
BRPF1 P55201 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HTR5A P47898 4/20 0.33
NOS2 P35228 1/20 0.33
EP300 Q09472 1/20 0.31
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
PARP3 Q9Y6F1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11751614 0.82 HTR5A (0.34) MEN1GAAMAPTALOX15CASP1
SCHEMBL11748932 0.77 HTR5A (0.36) MEN1GAAMAPTALOX15CASP1
SCHEMBL11750901 0.75 GAA (0.38) MEN1GAAMAPTALOX15CASP1
SCHEMBL11749109 0.74 CNR2 (0.34) MEN1GAAMAPTALOX15CASP1
SCHEMBL11753669 0.73 CREBBP (0.40) MEN1GAAMAPTALOX15CASP1
SCHEMBL13892507 0.65 MEN1 (0.37) MEN1GAAMAPTALOX15CASP1
SCHEMBL8288268 0.64 CREBBP (0.46) MEN1GAAMAPTALOX15CASP1
SCHEMBL4533080 0.64 CREBBP (0.35) MEN1GAAMAPTALOX15CASP1
SCHEMBL21669403 0.61 MAPT (0.41) MEN1GAAMAPTALOX15CASP1
SCHEMBL8279432 0.60 CREBBP (0.50) MEN1GAAMAPTALOX15CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11872244-B2 Thixotropic oxidized cellulose solutions and medical applications thereof COVIDIEN LP (US) 2024-01-16 US disclosed
US-11873350-B2 Dissolution of oxidized cellulose COVIDIEN LP (US) 2024-01-16 US disclosed
EP-3085396-B1 RESORBABLE OXIDIZED CELLULOSE EMBOLIZATION SOLUTION COVIDIEN LP (US) 2022-07-20 EP disclosed
US-20210238314-A1 DISSOLUTION OF OXIDIZED CELLULOSE COVIDIEN LP 2021-08-05 US disclosed
US-11065204-B2 Oxidized cellulose microspheres COVIDIEN LP (US) 2021-07-20 US disclosed
US-11053323-B2 Dissolution of oxidized cellulose and particle preparation by cross-linking with multivalent cations COVIDIEN LP (US) 2021-07-06 US disclosed
EP-3103442-B1 MICROSPHERES INCLUDING OXIDIZED CELLULOSE COVIDIEN LP (US) 2021-05-12 EP disclosed
US-10982012-B2 Dissolution of oxidized cellulose COVIDIEN LP (US) 2021-04-20 US disclosed
EP-3111928-B1 MICROSPHERES INCLUDING OXIDIZED CELLULOSE COVIDIEN LP (US) 2020-12-23 EP disclosed
US-10584184-B2 Medical devices based on oxidized cellulose COVIDIEN LP (US) 2020-03-10 US disclosed
EP-2708226-A1 Multi-Encapsulated Formulations Made With Oxidized Cellulose Covidien LP (US) 2014-03-19 EP disclosed
US-20140005376-A1 Dissolution of Oxidized Cellulose and Particle Preparation by Solvent and Non-Solvent Precipitation COVIDIEN LP (US) 2014-01-02 US disclosed
US-20140005378-A1 Dissolution of Oxidized Cellulose and Particle Preparation by Cross-Linking With Multivalent Cations COVIDIEN LP (US) 2014-01-02 US disclosed
US-20140005375-A1 Medical Devices Based On Oxidized Cellulose COVIDIEN LP (US) 2014-01-02 US disclosed
US-20140005377-A1 Dissolution of Oxidized Cellulose and Particle Preparation by Dispersion and Neutralization COVIDIEN LP (US) 2014-01-02 US disclosed
US-20130323312-A1 Microspheres Including Oxidized Cellulose CONFLUENT SURGICAL, INC. (US) 2013-12-05 US disclosed
US-20130323315-A1 Microspheres Including Oxidized Cellulose CONFLUENT SURGICAL, INC. (US) 2013-12-05 US disclosed
EP-2668942-A1 Microspheres including oxidized cellulose Confluent Surgical, Inc. (US) 2013-12-04 EP disclosed
EP-2668943-A1 Microspheres including oxidized cellulose Confluent Surgical, Inc. (US) 2013-12-04 EP disclosed
US-4016113-A AROMATIC AND ALKYL SUBSTITUTED AROMATIC ORTHO DIAMINES OLIN CORPORATION (US) 1977-04-05 US disclosed