Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.64 |
| ▸ | NPC1 | O15118 | 11/20 | 0.64 |
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | GFER | P55789 | 2/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2244339 | 0.90 | RAB9A (0.68) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11746959 | 0.88 | ESR2 (0.52) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL12210849 | 0.85 | RAB9A (0.79) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL12209688 | 0.83 | RAB9A (0.77) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11157432 | 0.81 | RAB9A (0.64) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11746181 | 0.81 | RAB9A (0.64) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL2244352 | 0.79 | NPC1 (0.76) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1734841 | 0.79 | NPC1 (0.76) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL29622897 | 0.79 | NPC1 (0.76) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL2242550 | 0.79 | HDAC6 (0.52) | RAB9ANPC1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024125-A | Dis-azo pigments deriving from bis-diazotized diamino-2-phenyl-benzazolones | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |