Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.52 |
| ▸ | ESR1 | P03372 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748987 | 0.88 | RAB9A (0.64) | ESR2ESR1NPC1RAB9AALDH1A1 | |
| SCHEMBL2242550 | 0.82 | HDAC6 (0.52) | ESR2ESR1NPC1RAB9AALDH1A1 | |
| SCHEMBL2244339 | 0.78 | RAB9A (0.68) | ESR2ESR1NPC1RAB9AALDH1A1 | |
| SCHEMBL2244141 | 0.74 | NPC1 (0.71) | ESR2ESR1NPC1RAB9AALDH1A1 | |
| SCHEMBL2240635 | 0.74 | RAB9A (0.71) | ESR2ESR1NPC1RAB9AALDH1A1 | |
| SCHEMBL31631311 | 0.74 | NPC1 (0.64) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL12997104 | 0.74 | KDM4E (0.64) | ESR2ESR1NPC1RAB9AALDH1A1 | |
| SCHEMBL2245161 | 0.74 | RAB9A (0.66) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30358946 | 0.74 | PTGS2 (0.55) | ESR2ESR1NPC1RAB9AALDH1A1 | |
| SCHEMBL31154233 | 0.73 | NPC1 (0.49) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024125-A | Dis-azo pigments deriving from bis-diazotized diamino-2-phenyl-benzazolones | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |