Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11752678 | 0.95 | PPARA (0.38) | PPARAPPARGSLC6A4CYP2C19LMNA | |
| SCHEMBL11757005 | 0.91 | PPARG (0.40) | PPARAPPARGSLC6A4HTR2APPARD | |
| SCHEMBL11752410 | 0.91 | PPARG (0.43) | PPARAPPARGCYP2C9CYP2C19PPARD | |
| SCHEMBL11746557 | 0.86 | ALDH1A1 (0.42) | PPARAPPARGSLC6A4CYP2C9CYP2C19 | |
| SCHEMBL11747760 | 0.85 | PPARA (0.47) | PPARAPPARGHTR2ACYP2C19MAPT | |
| SCHEMBL11755471 | 0.85 | PPARG (0.49) | PPARAPPARGPPARDLMNAALDH1A1 | |
| SCHEMBL11749185 | 0.81 | PPARA (0.38) | PPARAPPARGPTGDR2CYP2C9CYP2C19 | |
| SCHEMBL11754896 | 0.81 | MEN1 (0.38) | PPARAPPARGSLC6A4CYP2C19PPARD | |
| SCHEMBL11750435 | 0.80 | PPARA (0.50) | PPARAPPARGHTR2ACYP2C19MAPT | |
| SCHEMBL11753169 | 0.77 | PPARG (0.40) | PPARAPPARGSLC6A4MAPTSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051173-A | Phenoxyalkanol derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |