Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11752678 | 0.95 | PPARA (0.38) | PPARGPPARASLC6A4 | |
| SCHEMBL11749170 | 0.91 | PPARA (0.39) | PPARGPPARAPPARDFFAR1HTR2A | |
| SCHEMBL11753169 | 0.86 | PPARG (0.40) | PPARGPPARALTA4HPDK1PDK2 | |
| SCHEMBL11752082 | 0.85 | PPARA (0.47) | PPARGPPARALTA4HEPHX2HTR2A | |
| SCHEMBL11755471 | 0.85 | PPARG (0.49) | PPARGPPARAPPARDLTA4HEPHX2 | |
| SCHEMBL11749695 | 0.81 | PPARG (0.41) | PPARGPPARAPPARDLTA4HEPHX2 | |
| SCHEMBL11754896 | 0.81 | MEN1 (0.38) | PPARGPPARAPPARDSLC6A4 | |
| SCHEMBL11752410 | 0.81 | PPARG (0.43) | PPARGPPARAPPARD | |
| SCHEMBL11750435 | 0.80 | PPARA (0.50) | PPARGPPARAHTR2A | |
| SCHEMBL11746557 | 0.77 | ALDH1A1 (0.42) | PPARGPPARAPPARDFFAR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051173-A | Phenoxyalkanol derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |