Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830034 | 0.80 | TSHR (0.44) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29286 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11128036 | 0.72 | KDM4E (0.47) | KDM4EGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL9592615 | 0.70 | CTNNB1 (0.61) | KDM4EALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL28748733 | 0.68 | POLB (0.54) | KDM4EGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL11133778 | 0.68 | MEN1 (0.48) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29840068 | 0.68 | GAA (0.67) | KDM4EGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL3928666 | 0.68 | GAA (0.67) | KDM4EGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL10559219 | 0.67 | RAB9A (0.64) | ALDH1A1RAB9ANPC1SMN1; SMN2P2RY1 | |
| SCHEMBL9275209 | 0.66 | ELANE (0.44) | KDM4EGAAALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001234-A | SUBSTITUTED PYRIMIDINYLOXY(THIO)PHENYL UREAS AND DERIVATIVES THEREOF | THE DOW CHEMICAL COMPANY (US) | 1977-01-04 | — | — | US | disclosed |